\u8a8d\u77e5\u75c7\u306e\u6cbb\u7642
\n\u30ec\u30ab\u30cd\u30de\u30d6\u6642\u4ee3\u306b\u518d\u8003\u3059\u308b\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u6cbb\u7642\uff1a\u30a2\u30df\u30ed\u30a4\u30c9\u4f4e\u4e0b\u3068\u81e8\u5e8a\u52b9\u679c\u306e\u4e56\u96e2\u3001\u305d\u3057\u3066\u7d71\u5408\u7684\u6cbb\u7642\u6226\u7565\u306e\u5fc5\u7136\u6027<\/p>\n
1. \u306f\u3058\u3081\u306b\uff1a\u30a2\u30df\u30ed\u30a4\u30c9\u4eee\u8aac\u306e\u9650\u754c\u3068\u6cbb\u7642\u30d1\u30e9\u30c0\u30a4\u30e0\u306e\u8ee2\u63db**
\n\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\uff08AD\uff09\u6cbb\u7642\u306f\u9577\u3089\u304f\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\uff08A\u03b2\uff09\u3092\u4e3b\u8981\u6a19\u7684\u3068\u3057\u3066\u304d\u305f\u304c\u3001\u8fd1\u5e74\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u84c4\u7a4d\u306b\u3088\u308a\u3001**A\u03b2\u4f4e\u4e0b\uff1d\u8a8d\u77e5\u6a5f\u80fd\u6539\u5584**\u3068\u3044\u3046\u5358\u7d14\u306a\u69cb\u56f3\u306f\u6210\u7acb\u3057\u306a\u3044\u3053\u3068\u304c\u660e\u78ba\u306b\u306a\u308a\u3064\u3064\u3042\u308b\u3002<\/p>\n
\u300c\u30a2\u30df\u30ed\u30a4\u30c9\u03b2(A\u03b2)\u3092\u6291\u3048\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u69d8\u3005\u306a\u6cbb\u7642\u304c\u8a66\u307f\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3053\u306e\u65b9\u6cd5\u3060\u3051\u3067\u306f\u3001\u52b9\u679c\u304c\u4e0d\u5341\u5206\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u300d<\/p>\n
\u3053\u306e\u8a8d\u8b58\u306f\u3001\u30ec\u30ab\u30cd\u30de\u30d6\u3092\u542b\u3080\u6297\u30a2\u30df\u30ed\u30a4\u30c9\u6297\u4f53\u306e\u81e8\u5e8a\u30c7\u30fc\u30bf\u89e3\u91c8\u306b\u3082\u76f4\u7d50\u3059\u308b\u3002<\/p>\n
<\/p>\n
2. \u6297\u30a2\u30df\u30ed\u30a4\u30c9\u85ac\u306b\u304a\u3051\u308b\u201c\u30a2\u30df\u30ed\u30a4\u30c9\u4f4e\u4e0b\u201d\u3068\u201c\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u6291\u5236\u201d\u306e\u76f8\u95a2\u306f\u5f31\u3044**<\/p>\n
\u30e1\u30bf\u89e3\u6790\u30fb\u7dcf\u8aac\u304c\u793a\u3059\u4e00\u8cab\u3057\u305f\u7d50\u8ad6
\n\u8907\u6570\u306e\u30ec\u30d3\u30e5\u30fc\u306f\u3001A\u03b2\u4f4e\u4e0b\u3068\u8a8d\u77e5\u6a5f\u80fd\u306e\u6539\u5584\u304c\u5f37\u56fa\u306b\u7d50\u3073\u3064\u304b\u306a\u3044\u3053\u3068\u3092\u660e\u78ba\u306b\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n
\u25cf Ackley 2021\uff08JAMA Neurology\uff09
\n– \u6297\u30a2\u30df\u30ed\u30a4\u30c9\u85ac\u306eRCT\u3092\u7d71\u5408\u89e3\u6790
\n– **PET\u3067\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u4f4e\u4e0b\u91cf\u3068\u8a8d\u77e5\u6a5f\u80fd\u5909\u5316\u306e\u9593\u306b\u6709\u610f\u306a\u76f8\u95a2\u306f\u8a8d\u3081\u3089\u308c\u305a**
\n– A\u03b2\u306f\u30b5\u30ed\u30b2\u30fc\u30c8\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u59a5\u5f53\u6027\u4e0d\u5341\u5206<\/p>\n
> \u300c\u30a2\u30df\u30ed\u30a4\u30c9\u8ca0\u8377\u306e\u6e1b\u5c11\u304c\u81e8\u5e8a\u7684\u6539\u5584\u306b\u4e00\u8cab\u3057\u3066\u7d50\u3073\u3064\u304f\u6709\u610f\u306a\u95a2\u9023\u306f\u793a\u3055\u308c\u305a\u300d
\n\uff08\u30ec\u30ab\u30cd\u30de\u30d6\u6587\u66f8\u3088\u308a\uff09<\/p>\n
\u25cf Schneider 2019
\n– \u30a2\u30df\u30ed\u30a4\u30c9\u4eee\u8aac\u306e\u81e8\u5e8a\u7684\u9650\u754c\u3092\u6307\u6458
\n– \u30bf\u30a6\u3001\u708e\u75c7\u3001\u8840\u7ba1\u56e0\u5b50\u306a\u3069\u591a\u56e0\u5b50\u6027\u304c\u76f8\u95a2\u3092\u5f31\u3081\u308b<\/p>\n
\u25cf Murphy & Levine
\n– A\u03b2\u4f4e\u4e0b\u304c\u81e8\u5e8a\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u7dda\u5f62\u306b\u7d50\u3073\u3064\u304b\u306a\u3044\u53ef\u80fd\u6027\u3092\u5f37\u8abf<\/p>\n
—<\/p>\n
3. \u30ec\u30ab\u30cd\u30de\u30d6\uff08CLARITY-AD\uff09\u306b\u304a\u3051\u308b\u76f8\u95a2\u306e\u554f\u984c**
\n\u30ec\u30ab\u30cd\u30de\u30d6\u306f\u7fa4\u9593\u5e73\u5747\u3068\u3057\u3066CDR-SB\u306e\u4f4e\u4e0b\u6291\u5236\u3092\u793a\u3057\u305f\u304c\u3001**\u500b\u4f53\u30ec\u30d9\u30eb\u306e\u76f8\u95a2\u306f\u5c0f\u3055\u3044**\u3002<\/p>\n
– \u30a2\u30df\u30ed\u30a4\u30c9PET\u306e\u6539\u5584\u3068\u8a8d\u77e5\u30b9\u30b3\u30a2\u5909\u5316\u306e\u6563\u5e03\u56f3\u306f\u5927\u304d\u306a\u3070\u3089\u3064\u304d
\n– \u300c\u7d71\u8a08\u7684\u6709\u610f\u300d\u3068\u300c\u500b\u5225\u60a3\u8005\u306e\u610f\u5473\u306e\u3042\u308b\u6539\u5584\u300d\u306f\u7570\u306a\u308b\u6982\u5ff5
\n– \u52b9\u679c\u91cf\u306f\u5c0f\u3055\u304f\u3001\u81e8\u5e8a\u7684\u610f\u7fa9\u306f\u614e\u91cd\u306b\u8a55\u4fa1\u3059\u3079\u304d<\/p>\n
> \u300c\u30a2\u30df\u30ed\u30a4\u30c9\u6e1b\u5c11\u91cf\u3068\u8a8d\u77e5\u30b9\u30b3\u30a2\u5909\u5316\u306e\u6563\u5e03\u56f3\u306f\u76f8\u5f53\u306a\u3070\u3089\u3064\u304d\u3092\u793a\u3059\u3002\u300d
\n\uff08\u30ec\u30ab\u30cd\u30de\u30d6\u6587\u66f8\u3088\u308a\uff09<\/p>\n
—<\/p>\n
4. \u306a\u305c\u76f8\u95a2\u304c\u5f31\u3044\u306e\u304b\uff1a\u75c5\u614b\u751f\u7269\u5b66\u7684\u80cc\u666f**<\/p>\n
4-1. \u30bf\u30a6\u75c5\u7406\u306e\u4e3b\u5c0e\u6027**
\n\u3001
\n**\u300c\u30bf\u30a6\u304c\u7570\u5e38\u306b\u30ea\u30f3\u9178\u5316\u3055\u308c\u2026\u795e\u7d4c\u539f\u7dda\u7dad\u5909\u5316\u304c\u75c5\u6c17\u306e\u9032\u884c\u306b\u6df1\u304f\u95a2\u308f\u3063\u3066\u3044\u308b\u300d**\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5.pdf\uff09<\/p>\n
\u30bf\u30a6PET\u3084CSF\u30bf\u30a6\u306f\u8a8d\u77e5\u4f4e\u4e0b\u3068\u5f37\u304f\u76f8\u95a2\u3057\u3001A\u03b2\u306f\u3088\u308a\u65e9\u671f\u306e\u201c\u5fc5\u8981\u6761\u4ef6\u201d\u306b\u8fd1\u3044\u3002
\nA\u03b2\u3092\u9664\u53bb\u3057\u3066\u3082\u3001\u30bf\u30a6\u4f1d\u64ad\u30fb\u795e\u7d4c\u7d30\u80de\u6b7b\u306f\u9032\u884c\u3057\u3046\u308b\u3002<\/p>\n
4-2. \u6df7\u5408\u75c5\u7406\uff08TDP-43\u3001\u03b1\u30b7\u30cc\u30af\u30ec\u30a4\u30f3\u3001\u8840\u7ba1\u75c5\u5909\uff09**
\n\u9ad8\u9f62\u8005\u306eAD\u306f\u5358\u4e00\u75c5\u7406\u3067\u306f\u306a\u304f\u3001A\u03b2\u3060\u3051\u3067\u306f\u8a8d\u77e5\u5909\u5316\u3092\u8aac\u660e\u3067\u304d\u306a\u3044\u3002<\/p>\n
4-3. \u52a0\u9f62\u3068\u30b0\u30ea\u30a2\u7d30\u80de\u306e\u8001\u5316**
\nPDF\u6587\u66f8\u304c\u6307\u6458\u3059\u308b\u3088\u3046\u306b\u3001
\n\u300c\u30b0\u30ea\u30a2\u7d30\u80de\u304c\u52a0\u9f62\u3068\u3068\u3082\u306b\u8001\u5316\u3057\u3001\u8133\u6a5f\u80fd\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3059\u300d**\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5.pdf\uff09<\/p>\n
\u795e\u7d4c\u708e\u75c7\u30fb\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u6d3b\u6027\u5316\u306fA\u03b2\u3068\u306f\u72ec\u7acb\u3057\u3066\u8a8d\u77e5\u4f4e\u4e0b\u306b\u5bc4\u4e0e\u3059\u308b\u3002<\/p>\n
–<\/p>\n
5. \u907a\u4f1d\u8981\u56e0\uff08APOE \u03b54\uff09\u3068\u6cbb\u7642\u53cd\u5fdc\u6027\u306e\u591a\u69d8\u6027**
\nAPOE \u03b54\u306fA\u03b2\u6c88\u7740\u3060\u3051\u3067\u306a\u304f\u3001\u30bf\u30a6\u75c5\u7406\u30fb\u8840\u7ba1\u75c5\u7406\u30fb\u708e\u75c7\u306b\u3082\u5f71\u97ff\u3059\u308b\u3002
\nPDF\u6587\u66f8\u306e\u901a\u308a\u3001
\n\u300c\u4eba\u7a2e\u3084\u7956\u5148\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u907a\u4f1d\u5b50\u9818\u57df\u306e\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u308b\u300d**\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5.pdf\uff09<\/p>\n
\u907a\u4f1d\u80cc\u666f\u306e\u9055\u3044\u304c\u3001A\u03b2\u4f4e\u4e0b\u3068\u81e8\u5e8a\u52b9\u679c\u306e\u76f8\u95a2\u3092\u3055\u3089\u306b\u8907\u96d1\u5316\u3055\u305b\u308b\u3002<\/p>\n
<\/p>\n
*6. \u7d71\u5408\u7684\u6cbb\u7642\u6226\u7565\u306e\u5fc5\u8981\u6027\uff1a\u5358\u4e00\u6a19\u7684\u3067\u306f\u4e0d\u5341\u5206**<\/p>\n
<\/p>\n
\u300c\u4e00\u3064\u306e\u8981\u56e0\u3060\u3051\u3092\u898b\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u7d71\u5408\u7684\u306a\u6226\u7565\u306b\u79fb\u884c\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u300d**\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5.pdf\uff09<\/p>\n
### \u25cf \u7d71\u5408\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u69cb\u6210\u8981\u7d20
\n– \u6297\u30a2\u30df\u30ed\u30a4\u30c9\u85ac\uff08\u30ec\u30ab\u30cd\u30de\u30d6\u7b49\uff09\uff1a\u75c5\u7406\u9032\u884c\u6291\u5236\u306e\u4e00\u90e8
\n– \u30bf\u30a6\u75c5\u7406\u3078\u306e\u4ecb\u5165\uff08\u958b\u767a\u4e2d\uff09
\n– \u8840\u7ba1\u30ea\u30b9\u30af\u7ba1\u7406\uff08\u9ad8\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u3001\u8102\u8cea\u7570\u5e38\u75c7\uff09
\n– \u8a8d\u77e5\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3
\n– \u8eab\u4f53\u6d3b\u52d5\u30fb\u7761\u7720\u30fb\u6804\u990a
\n– \u793e\u4f1a\u7684\u6d3b\u52d5\u30fb\u7cbe\u795e\u7684\u5065\u5eb7
\n– \u30b0\u30ea\u30a2\u7d30\u80de\u8001\u5316\u3078\u306e\u4ecb\u5165\uff08\u7814\u7a76\u6bb5\u968e\uff09
\n– \u907a\u4f1d\u5b50\u6cbb\u7642\uff08\u5c06\u6765\u306e\u53ef\u80fd\u6027\uff09<\/p>\n
<\/p>\n
7. \u81e8\u5e8a\u73fe\u5834\u3067\u306e\u5b9f\u52d9\u7684\u30dd\u30a4\u30f3\u30c8**<\/p>\n
\u25cf 1\uff09\u30a2\u30df\u30ed\u30a4\u30c9PET\u306f\u300c\u52b9\u3044\u3066\u3044\u308b\u304b\u306e\u751f\u7269\u5b66\u7684\u6307\u6a19\u300d\u306b\u3059\u304e\u306a\u3044
\n\u81e8\u5e8a\u52b9\u679c\u306e\u4fdd\u8a3c\u3067\u306f\u306a\u3044\u3002<\/p>\n
\u25cf 2\uff09\u60a3\u8005\u30fb\u5bb6\u65cf\u3078\u306e\u8aac\u660e\u3067\u306f\u201c\u6a5f\u80fd\u6307\u6a19\u201d\u3092\u4e3b\u8a9e\u306b\u3059\u308b
\n– CDR-SB
\n– ADCS-MCI-ADL
\n– FAQ\uff08\u6a5f\u80fd\u8a55\u4fa1\uff09<\/p>\n
\u25cf 3\uff09\u30ec\u30ab\u30cd\u30de\u30d6\u306e\u76ee\u7684\u306f\u300c\u6539\u5584\u300d\u3067\u306f\u306a\u304f\u300c\u9032\u884c\u6291\u5236\u306e\u78ba\u7387\u3092\u4e0a\u3052\u308b\u300d
\n\u904e\u5ea6\u306a\u671f\u5f85\u3092\u907f\u3051\u308b\u3002<\/p>\n
\u25cf 4\uff09ARIA\u76e3\u8996\u30fb\u901a\u9662\u8ca0\u62c5\u30fb\u8cbb\u7528\u3092\u542b\u3081\u305f\u7dcf\u5408\u5224\u65ad
\n\u30ea\u30bf\u30fc\u30f3\u3068\u8ca0\u62c5\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u900f\u660e\u306b\u5171\u6709\u3059\u308b\u3002<\/p>\n
-# **\u7dcf\u5408\u7d50\u8ad6**
\n\u30ec\u30ab\u30cd\u30de\u30d6\u3092\u542b\u3080\u6297\u30a2\u30df\u30ed\u30a4\u30c9\u85ac\u306f\u3001A\u03b2\u75c5\u7406\u306e\u6539\u5584\u3092\u78ba\u5b9f\u306b\u793a\u3059\u4e00\u65b9\u3067\u3001**\u8a8d\u77e5\u6a5f\u80fd\u6539\u5584\u3068\u306e\u5f37\u56fa\u306a\u76f8\u95a2\u306f\u78ba\u8a8d\u3055\u308c\u3066\u3044\u306a\u3044**\u3002
\n\u3053\u308c\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u304c**\u30bf\u30a6\u75c5\u7406\u3001\u708e\u75c7\u3001\u8840\u7ba1\u56e0\u5b50\u3001\u907a\u4f1d\u3001\u52a0\u9f62\u3001\u6df7\u5408\u75c5\u7406**\u306a\u3069\u591a\u56e0\u5b50\u6027\u306e\u75be\u60a3\u3067\u3042\u308b\u305f\u3081\u3067\u3042\u308b\u3002<\/p>\n
\u3057\u305f\u304c\u3063\u3066\u3001\u6cbb\u7642\u306f\u5358\u4e00\u6a19\u7684\u3067\u306f\u306a\u304f\u3001
\n**\u300c\u7d71\u5408\u7684\u30fb\u591a\u9762\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u300d\u3053\u305d\u304c\u73fe\u5b9f\u7684\u304b\u3064\u79d1\u5b66\u7684\u306b\u59a5\u5f53\u306a\u6226\u7565**\u3067\u3042\u308b\u3002<\/p>\n
\u4e0a\u8a18\u306f\u307b\u307cAI\u306b\u3088\u3063\u3066\u307e\u3068\u3081\u3089\u308c\u305f\u6587\u7ae0\u3067\u3059\u304c\u3001\u79c1\u3082\u307b\u307c\u8cdb\u540c\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"
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